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HSC70 antibody [N2C1], Internal

GTX111069
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetHSPA8
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Overview

  • Supplier
    GeneTex
  • Product Name
    HSC70 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3312
  • Target name
    HSPA8
  • Target description
    heat shock protein family A (Hsp70) member 8
  • Target synonyms
    HEL-33, HEL-S-72p, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP-1, LAP1, NIP71, heat shock cognate 71 kDa protein, LPS-associated protein 1, N-myristoyltransferase inhibitor protein 71, constitutive heat shock protein 70, epididymis luminal protein 33, epididymis secretory sperm binding protein Li 72p, heat shock 70kDa protein 8, heat shock 70kd protein 10, heat shock cognate protein 54, heat shock protein family A member 8, lipopolysaccharide-associated protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP11142
  • Protein Name
    Heat shock cognate 71 kDa protein
  • Scientific Description
    The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fussi N, Höllerhage M, Chakroun T, et al. Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy. Cell Death Dis. 2018,9(7):757. doi: 10.1038/s41419-018-0816-2
    Read this paper
  • Soliman M, Seo JY, Kim DS, et al. Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoating. PLoS Pathog. 2018,14(1):e1006820. doi: 10.1371/journal.ppat.1006820
    Read this paper
  • Luu BE, Wijenayake S, Malik AI, et al. The regulation of heat shock proteins in response to dehydration in Xenopus laevis. Cell Stress Chaperones. 2018,23(1):45-53. doi: 10.1007/s12192-017-0822-9
    Read this paper