Western blot analysis of extracts of Mouse liver using HSD11B1 Polyclonal Antibody at dilution of 1:1000.
HSD11 beta Polyclonal Antibody
E-AB-61779
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHSD11 beta Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
- UNSPSC12352203