HSD17B13-IN-27 [2758802-31-0]

TargetMol Chemicals

HSD17B13-IN-27 [2758802-31-0]

16

Research Use Only

C21H19FN2O4S

414.45

HSD17B13-IN-27 (compound 30) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 microM and approximately less than 1 microM for estradiol and Leukotriene B3, respectively, as substrates. This compound is crucial in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

C(NCCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(F)=C(O)C=C3)C=CS2

-20°C

51202000