HSD17B13-IN-30 [2770246-58-5]

TargetMol Chemicals

HSD17B13-IN-30 [2770246-58-5]

16

Research Use Only

C24H16Cl2F3N3O4

538.3

HSD17B13-IN-30 (compound 64) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 value of less than 0.1 microM? with estradiol? as substrates. This compound is significantly implicated in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=CC=C2

-20°C

51202000