HSD17B13-IN-40 [2770246-06-3]

TargetMol Chemicals

HSD17B13-IN-40 [2770246-06-3]

16

Research Use Only

C23H14Cl2F3N3O3

508.28

HSD17B13-IN-40 (compound 6) serves as a potent inhibitor of hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 microM using estradiol as substrates. This compound is significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=CC=C(C(F)(F)F)C=C4)C3=O)=CC=C2

-20°C

51202000