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IHC-P analysis of human liver using GTX89330 HSD3a antibody, N-term. Antigen retrieval : citrate buffer pH 6 Dilution : 2.5microg/ml
IHC-P analysis of human liver using GTX89330 HSD3a antibody, N-term. Antigen retrieval : citrate buffer pH 6 Dilution : 2.5microg/ml
IHC-P analysis of human liver using GTX89330 HSD3a antibody, N-term. Antigen retrieval : citrate buffer pH 6 Dilution : 2.5microg/ml

HSD3a antibody, N-term

GTX89330
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetAKR1C4
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Overview

  • Supplier
    GeneTex
  • Product Name
    HSD3a antibody, N-term
  • Delivery Days Customer
    7
  • Application Supplier Note
    WB: 0.1-0.3microg/ml. IHC-P: 2-4microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1109
  • Target name
    AKR1C4
  • Target description
    aldo-keto reductase family 1 member C4
  • Target synonyms
    3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA, aldo-keto reductase family 1 member C4, 3-alpha-HSD1, 3alpha-hydroxysteroid 3-dehydrogenase, chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4, dihydrodiol dehydrogenase isozyme DD4, type I 3-alpha-hydroxysteroid dehydrogenase
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP17516
  • Protein Name
    Aldo-keto reductase family 1 member C4
  • Scientific Description
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Guo SS, Chen YZ, Liu LT, et al. Prognostic significance of AKR1C4 and the advantage of combining EBV DNA to stratify patients at high risk of locoregional recurrence of nasopharyngeal carcinoma. BMC Cancer. 2022,22(1):880. doi: 10.1186/s12885-022-09924-3
    Read this paper