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IHC-P analysis of human liver using GTX89330 HSD3a antibody, N-term. Antigen retrieval : citrate buffer pH 6 Dilution : 2.5microg/ml
IHC-P analysis of human liver using GTX89330 HSD3a antibody, N-term. Antigen retrieval : citrate buffer pH 6 Dilution : 2.5microg/ml
IHC-P analysis of human liver using GTX89330 HSD3a antibody, N-term. Antigen retrieval : citrate buffer pH 6 Dilution : 2.5microg/ml

HSD3a antibody, N-term

GTX89330
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetAKR1C4
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Overview

  • Supplier
    GeneTex
  • Product Name
    HSD3a antibody, N-term
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody may cross-react with AKR1C1
  • Application Supplier Note
    WB: 0.1-0.3microg/ml. IHC-P: 2-4microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1109
  • Target name
    AKR1C4
  • Target description
    aldo-keto reductase family 1 member C4
  • Target synonyms
    3-alpha-HSD; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; aldo-keto reductase family 1 member C4; C11; CDR; CHDR; chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4; DD4; DD-4; dihydrodiol dehydrogenase isozyme DD4; HAKRA; type I 3-alpha-hydroxysteroid dehydrogenase
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP17516
  • Protein Name
    Aldo-keto reductase family 1 member C4
  • Scientific Description
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Prognostic significance of AKR1C4 and the advantage of combining EBV DNA to stratify patients at high risk of locoregional recurrence of nasopharyngeal carcinoma.
    Read more