Hsp70 antibody
GTX111088
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityC. Elegans, Human, Monkey, Mouse, Rat
TargetHSPA1A
Overview
- SupplierGeneTex
- Product NameHsp70 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.62 mg/ml
- ConjugateUnconjugated
- Gene ID3303
- Target nameHSPA1A
- Target descriptionheat shock protein family A (Hsp70) member 1A
- Target synonymsHEL-S-103, HSP70, HSP70-1, HSP70-1A, HSP70-2, HSP70.1, HSP70.2, HSP70I, HSP72, HSPA1, heat shock 70 kDa protein 1A, HSP70-1/HSP70-2, HSP70.1/HSP70.2, Heat shock 70 kDa protein 1B, Heat shock 70 kDa protein 2, dnaK-type molecular chaperone HSP70-1, epididymis secretory protein Li 103, epididymis secretory sperm binding protein, heat shock 70 kDa protein 1, heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A/1B, heat shock 70kD protein 1A, heat shock 70kDa protein 1A, heat shock protein family A member 1A, heat shock-induced protein
- HostRabbit
- IsotypeIgG
- Protein IDP0DMV8
- Protein NameHeat shock 70 kDa protein 1A
- Scientific DescriptionThis intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq]
- ReactivityC. Elegans, Human, Monkey, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tang L, An P, Zhao Q, et al. Heat Shock Protein Family A Member 1 Promotes Intracellular Amplification of Hepatitis B Virus Covalently Closed Circular DNA. J Virol. 2023,97(1):e0126122. doi: 10.1128/jvi.01261-22Read this paper
- Kuo HH, Su ZR, Chuang JY, et al. Heat shock factor 1 suppression induces spindle abnormalities and sensitizes cells to antimitotic drugs. Cell Div. 2021,16(1):8. doi: 10.1186/s13008-021-00075-8Read this paper
- Chen WJ, Lin IH, Lee CW, et al. Aged Skeletal Muscle Retains the Ability to Remodel Extracellular Matrix for Degradation of Collagen Deposition after Muscle Injury. Int J Mol Sci. 2021,22(4). doi: 10.3390/ijms22042123Read this paper
- Chen JF, Tsai YT, Lai YH, et al. Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. J Pharm Biomed Anal. 2020,187:113142. doi: 10.1016/j.jpba.2020.113142Read this paper
- Abo-Rady M, Kalmbach N, Pal A, et al. Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins. Stem Cell Reports. 2020,14(3):390-405. doi: 10.1016/j.stemcr.2020.01.010Read this paper
- Chen YF, Lin IH, Guo YR, et al. Rrm2b deletion causes mitochondrial metabolic defects in renal tubules. Sci Rep. 2019,9(1):13238. doi: 10.1038/s41598-019-49663-3Read this paper
- Tung H, Wei SC, Lo HR, et al. Baculovirus IE2 Stimulates the Expression of Heat Shock Proteins in Insect and Mammalian Cells to Facilitate Its Proper Functioning. PLoS One. 2016,11(2):e0148578. doi: 10.1371/journal.pone.0148578Read this paper
- Chen HY, Cheng YS, Shih HH. Expression patterns and structural modelling of Hsp70 and Hsp90 in a fish-borne zoonotic nematode Anisakis pegreffii. Vet Parasitol. 2015,212(3-4):281-91. doi: 10.1016/j.vetpar.2015.07.006Read this paper
- Gong H, Kobayashi K, Sugi T, et al. Characterization and binding analysis of a microneme adhesive repeat domain-containing protein from Toxoplasma gondii. Parasitol Int. 2014,63(2):381-8. doi: 10.1016/j.parint.2013.12.006Read this paper
![IHC-P analysis of human ovary adenocarcinoma tissue using GTX84337 Hsp70 antibody [1B2]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84337/GTX84337_2624_IHC-P_w_23061420_403.webp)
![ICC/IF analysis of COS7 cells transiently transfected with Hsp70 plasmid using GTX84338 Hsp70 antibody [3C6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84338/GTX84338_1042_ICCIF_w_23061420_652.webp)
![ICC/IF analysis of COS7 cells transiently transfected with Hsp70 plasmid using GTX84340 Hsp70 antibody [5F3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84340/GTX84340_1043_ICCIF_w_23061420_664.webp)
![ICC/IF analysis of COS7 cells transiently transfected with Hsp70 plasmid using GTX84341 Hsp70 antibody [2C12].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84341/GTX84341_1045_ICCIF_w_23061420_172.webp)

