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Hsp70 antibody

Research Use Only
GTX111088
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityC. Elegans, Human, Monkey, Mouse, Rat
TargetHSPA1A
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Overview

  • Supplier
    GeneTex
  • Product Name
    Hsp70 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.62 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID3303
  • Target name
    HSPA1A
  • Target description
    heat shock protein family A (Hsp70) member 1A
  • Target synonyms
    dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; epididymis secretory sperm binding protein; heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 2; heat shock 70kD protein 1A; heat shock 70kDa protein 1A; heat shock-induced protein; HEL-S-103; HSP70.1; HSP70.1/HSP70.2; HSP70.2; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-2; HSP70I; HSP72; HSPA1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP0DMV8
  • Protein Name
    Heat shock 70 kDa protein 1A
  • Scientific Description
    This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq]
  • Reactivity
    C. Elegans, Human, Monkey, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Heat shock factor 1 suppression induces spindle abnormalities and sensitizes cells to antimitotic drugs. Kuo HH et al., 2021 Dec 18, Cell Div
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  • Aged Skeletal Muscle Retains the Ability to Remodel Extracellular Matrix for Degradation of Collagen Deposition after Muscle Injury. Chen WJ et al., 2021 Feb 20, Int J Mol Sci
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  • Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. Chen JF et al., 2020 Aug 5, J Pharm Biomed Anal
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  • Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins. Abo-Rady M et al., 2020 Mar 10, Stem Cell Reports
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  • Rrm2b deletion causes mitochondrial metabolic defects in renal tubules. Chen YF et al., 2019 Sep 13, Sci Rep
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  • Baculovirus IE2 Stimulates the Expression of Heat Shock Proteins in Insect and Mammalian Cells to Facilitate Its Proper Functioning. Tung H et al., 2016, PLoS One
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  • Expression patterns and structural modelling of Hsp70 and Hsp90 in a fish-borne zoonotic nematode Anisakis pegreffii. Chen HY et al., 2015 Sep 15, Vet Parasitol
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  • Characterization and binding analysis of a microneme adhesive repeat domain-containing protein from Toxoplasma gondii. Gong H et al., 2014 Apr, Parasitol Int
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