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HSP70-IN-1 [1268273-90-0]

HSP70-IN-1 [1268273-90-0]

T3487
TargetMol Chemicals
CAS Number1268273-90-0
Product group Chemicals
Molecular Weight464.58
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    HSP70-IN-1 [1268273-90-0]
  • Delivery Days Customer
    4
  • CAS Number
    1268273-90-0
  • Certification
    Research Use Only
  • Chemical Name
    HSP70-IN-1
  • Molecular Formula
    C24H28N6O2S
  • Molecular Weight
    464.58
  • Scientific Description
    HSP70-IN-1 is a heat shock protein (HSP) inhibitor that suppresses the growth of Kasumi-1 cells with an IC50 of 2.3 microM.
  • Shelf life instruction
    3 years
  • SMILES
    CN1CCN(CC1)c1ncc(Sc2cccc(NC(=O)CN)c2)c(OCc2ccccc2)n1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Taldone T, Kang Y, Patel HJ, et al. Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70. J Med Chem. 2014,57(4):1208-24. doi: 10.1021/jm401552y
    Read this paper