HSP90-IN-11

TargetMol Chemicals

HSP90-IN-11

114

Chemical

Research Use Only

HSP90-IN-11

C27H30FN3O6

511.54

HSP90-IN-11 is a potent inhibitor of HSP90 and induces significant accumulation of the sub-G1 population. HSP90-IN-11 has a potent HSP90alpha inhibitory effect comparable to that of AUY-922 (Luminespib). In CRC and NSCLC cells, HSP90-IN-11 exhibited significant anti-proliferative activity in the double-digit nM range.HSP90-IN-11 was able to rapidly degrade client proteins EGFR and Akt in NSCLC cells.

3 years

-20°C

51202000