Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using Crystallin-alpha C Polyclonal Antibody at dilution 1:45
HSPB8 Polyclonal Antibody
E-AB-10378
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHSPB8 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
- UNSPSC12352203