Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using Crystallin-alpha C Polyclonal Antibody at dilution 1:45
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using Crystallin-alpha C Polyclonal Antibody at dilution 1:45
Crystallin-alpha C Polyclonal Antibody
E-AB-10378
ApplicationsImmunoHistoChemistry
Product group Antibodies
TargetHSPB8
Overview
- SupplierElabscience
- Product NameCrystallin-alpha C Polyclonal Antibody
- Delivery Days Customer12
- ApplicationsImmunoHistoChemistry
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID26353
- Target nameHSPB8
- Target descriptionheat shock protein family B (small) member 8
- Target synonymsCMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HMND2, HSP22, HSPB8-N1, HSPB8-N2, MFM13, heat shock protein beta-8, E2-induced gene 1 protein, alpha-crystallin C chain, heat shock 22kDa protein 8, heat shock 27kDa protein 8, heat shock protein family B member 8, protein kinase H11, small stress protein-like protein HSP22
- HostRabbit
- IsotypeIgG
- Protein IDQ9UJY1
- Protein NameHeat shock protein beta-8
- Scientific DescriptionThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
- Storage Instruction-20°C
- UNSPSC41116161