Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with HSPC142 antibody [GT2810] (GTX629878) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.
![C19orf62 antibody [GT2810] detects C19orf62 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: C19orf62 protein stained by C19orf62 antibody [GT2810] (GTX629878) diluted at 1:500. Blue: Hoechst 33342 staining.](https://www.genetex.com/upload/website/prouct_img/normal/GTX629878/GTX629878_41470_IFA_w_23061202_651.webp "C19orf62 antibody [GT2810] detects C19orf62 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: C19orf62 protein stained by C19orf62 antibody [GT2810] (GTX629878) diluted at 1:500. Blue: Hoechst 33342 staining.")
![Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with HSPC142 antibody [GT2810] (GTX629878) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX629878/GTX629878_41470_20220325_WB_B_w_23061202_128.webp "Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with HSPC142 antibody [GT2810] (GTX629878) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.")
Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with HSPC142 antibody [GT2810] (GTX629878) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.
HSPC142 antibody [GT2810]
GTX629878
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetBABAM1
Overview
- SupplierGeneTex
- Product NameHSPC142 antibody [GT2810]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT2810
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID29086
- Target nameBABAM1
- Target descriptionBRISC and BRCA1 A complex member 1
- Target synonymsC19orf62, HSPC142, MERIT40, NBA1, BRISC and BRCA1-A complex member 1, BRCA1-A complex subunit MERIT40, mediator of RAP80 interactions and targeting subunit of 40 kDa, mediator of Rap80 interactions and targeting 40 kDa, new component of the BRCA1-A complex, new component of the BRCAA1 A complex
- HostMouse
- IsotypeIgG2b
- Protein IDQ9NWV8
- Protein NameBRISC and BRCA1-A complex member 1
- Scientific DescriptionComponent of the BRCA1-A complex, a complex that specifically recognizes Lys-63-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes Lys-63-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves Lys-63-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the Lys-63-linked deubiquitinase activity mediated by BRCC3/BRCC36. component.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
Datasheet
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![Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with HSPC142 antibody [GT1251] (GTX629814) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX629814/GTX629814_41470_20220304_WB_w_23061202_751.webp)
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