HTRA2/OMI, Human (His)

MedChem Express

HTRA2/OMI, Human (His)

10

Research Use Only

91.80

HTRA2

HtrA serine peptidase 2

MGCA8, OMI, PARK13, PRSS25, serine protease HTRA2, mitochondrial, HtrA-like serine protease, Omi stress-regulated endoprotease, epididymis secretory sperm binding protein, high temperature requirement protein A2, protease, serine, 25, serine protease 25, serine proteinase OMI

Serine protease HTRA2, mitochondrial

HTRA2/OMI, a serine protease, crucially induces cell death via multiple mechanisms.It directly inhibits BIRC proteins, intensifying caspase activity, and can also induce cell death through a BIRC-independent, caspase-independent pathway, relying on its serine protease activity.Additionally, during apoptosis, it cleaves THAP5, promoting its degradation.Notably, isoform 2 lacks apparent proteolytic activity.HTRA2/OMI Protein, Human (His) is the recombinant human-derived HTRA2/OMI protein, expressed by E.coli , with C-His labeled tag.

-80°C

41116100