HTRA2/OMI, Human (His)
HY-P74876
Protein IDO43464
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameHTRA2/OMI, Human (His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity91.80
- Gene ID27429
- Target nameHTRA2
- Target descriptionHtrA serine peptidase 2
- Target synonymsepididymis secretory sperm binding protein; high temperature requirement protein A2; HtrA-like serine protease; MGCA8; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; PRSS25; serine protease 25; serine protease HTRA2, mitochondrial; serine proteinase OMI
- Protein IDO43464
- Protein NameSerine protease HTRA2, mitochondrial
- Scientific DescriptionHTRA2/OMI, a serine protease, crucially induces cell death via multiple mechanisms.It directly inhibits BIRC proteins, intensifying caspase activity, and can also induce cell death through a BIRC-independent, caspase-independent pathway, relying on its serine protease activity.Additionally, during apoptosis, it cleaves THAP5, promoting its degradation.Notably, isoform 2 lacks apparent proteolytic activity.HTRA2/OMI Protein, Human (His) is the recombinant human-derived HTRA2/OMI protein, expressed by E.coli , with C-His labeled tag.
- Storage Instruction-80°C
- UNSPSC41116100