HU 433

Biorbyt

HU 433

10

1220887-84-2

Research Use Only

98.00%

C27H42O3

414.62

HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNgamma-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.

O(C)C1=C([C@H]2[C@@]3(C(C)(C)[C@@](C3)(C(CO)=C2)[H])[H])C(OC)=CC(C(CCCCCC)(C)C)=C1

-20°C

12352200