HUHS2002 [1393102-59-4]
HY-116153
CAS Number1393102-59-4
Product group Chemicals
Molecular Weight276.37
Overview
- SupplierMedChem Express
- Product NameHUHS2002 [1393102-59-4]
- Delivery Days Customer9
- CAS Number1393102-59-4
- CertificationResearch Use Only
- Molecular FormulaC17H24O3
- Molecular Weight276.37
- Scientific DescriptionHUHS2002 is a free fatty acid derivative with the ability to enhance alpha7 cholinergic receptor activity. HUHS2002 enhances whole-cell membrane currents of alpha7 ACh receptors expressed in Xenopus oocytes in a concentration-dependent manner. The effects of HUHS2002 were blocked in the presence of the Ca2 /calmodulin-dependent protein kinase II (CaMKII) inhibitor KN-93. HUHS2002 activated CaMKII in cultured rodent hippocampal neurons, and this activation was abolished by KN-93. HUHS2002 also partially inhibited the activity of protein phosphatase 1 (PP1) in a cell-free PP1 activity assay[1].
- SMILESO=C(CCCOC1=CC=C(C=C1)/C=C/CCCCC)O
- UNSPSC12352200