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ProductsBack/Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) (Gln18-Ser740)

Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) (Gln18-Ser740)

LS-G140043
LifeSpan BioSciences
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) (Gln18-Ser740)
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor dont inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202