ProductsBack/Human ACTRIIB / ACVR2B Protein (Recombinant Fc) (Met1-Thr134)

Human ACTRIIB / ACVR2B Protein (Recombinant Fc) (Met1-Thr134)

Name: Human ACTRIIB / ACVR2B Protein (Recombinant Fc) (Met1-Thr134)
SKU: LS-G97124_L25
Availability: BackOrder

LS-G97124

Product group Proteins / Signaling Molecules

Overview

Supplier
LifeSpan BioSciences
Product Name
Human ACTRIIB / ACVR2B Protein (Recombinant Fc) (Met1-Thr134)
Delivery Days Customer
23
Certification
Research Use Only
Estimated Purity
>97%
Gene ID93
Target name
ACVR2B
Target description
activin A receptor type 2B
Target synonyms
ACTRIIB, ActR-IIB, HTX4, activin receptor type-2B, activin A receptor, type IIB
Scientific Description
The recombinant human ACVR2B/Fc chimera is a disulfide-linked homodimer generated after removal of the signal peptide. The reduced monomer comprises 354 amino acids and predicts a molecular mass of 40.0 kDa. As a result of glycosylation, the monomer migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions. A DNA sequence encoding the N-terminal segment (Met 1-Thr 134) from the extracellular domain of human ACVR2B (NP_001097.2) was expressed with the fused human IgG1 Fc region at the C-terminus.
Storage Instruction
-80°C
UNSPSC
41116100
Species
Human