Human AKR1C3 ELISA Kit

Arigo Biolaboratories

Human AKR1C3 ELISA Kit

23

ELISA

Intra-Assay CV: 4.8%Inter-Assay CV: 5.8%

78 pg/ml

~ 5 hours

Research Use Only

HRP

Aldo-keto reductase family 1 member C3

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

2°C to 8°C

41116100

Human