Bio-Connect

Human ANXA2 Protein (ANX-HE102)

ANX-HE102
KACTUS
Protein IDP07355
Product group Proteins
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Overview

  • Supplier
    KACTUS
  • Product Name
    Human ANXA2 Protein (ANX-HE102)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Protein IDP07355
  • Protein Name
    Annexin A2
  • Scientific Description
    ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202