Human ANXA2 Protein (ANX-HE102)
ANX-HE102
Protein IDP07355
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameHuman ANXA2 Protein (ANX-HE102)
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity>95%
- Protein IDP07355
- Protein NameAnnexin A2
- Scientific DescriptionANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202