Human B7-H5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human B7-H5 / Gi24 / VISTA Protein, Fc Tag
B75-H5259
Product group Proteins / Signaling Molecules
Overview
- SupplierACRObiosystems
- Product NameHuman B7-H5 / Gi24 / VISTA Protein, Fc Tag
- Delivery Days Customer4
- Category SupplierImmune Checkpoint Proteins
- CertificationResearch Use Only
- Estimated Purity95%
- FormatPowder
- Scientific DescriptionCharacteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.8 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Description: Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
- Shelf life instruction● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- SourceHuman B7-H5, Fc Tag (B75-H5259) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Ala 194 (Accession # AAH20568).
- Storage Instruction-20℃
- UNSPSC12352202