GTX68442-pro Image
Human BLNK protein
GTX68442-PRO
Overview
- SupplierGeneTex
- Product NameHuman BLNK protein
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration1 mg/ml
- Protein IDQ8WV28
- Protein NameB-cell linker protein
- Scientific DescriptionThis gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202