3microg Human BRDG1 protein (GTX68375-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
3microg Human BRDG1 protein (GTX68375-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Human BRDG1 protein, His tag
GTX68375-PRO
Overview
- SupplierGeneTex
- Product NameHuman BRDG1 protein
- Delivery Days Customer9
- Concentration1 mg/ml
- FormulationLiquid
- Protein IDQ9ULZ2
- Protein NameSignal-transducing adaptor protein 1
- Scientific DescriptionThe protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202