Human CD140b / PDGFRB ELISA Kit

Arigo Biolaboratories

Human CD140b / PDGFRB ELISA Kit

23

ELISA

Intra-Assay CV: < 10%Inter-Assay CV: < 10%

100 pg/ml

4 hours

Research Use Only

HRP

Platelet-derived growth factor receptor beta

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]

-20°C,2°C to 8°C

41116100

Human