Human CDA / Cytidine Deaminase Protein (Recombinant His)

LifeSpan BioSciences

Human CDA / Cytidine Deaminase Protein (Recombinant His)

23

Research Use Only

0.5 mg/ml

>90%

CDA

cytidine deaminase

CDD, cytidine deaminase, cytidine aminohydrolase, cytosine nucleoside deaminase, small cytidine deaminase

CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2-deoxycytidine for uMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

-20°C or -80°C,2°C to 8°C

41116100

Human