WB analysis of GTX00214-pro Human CX3CL1 protein (active).
Human CX3CL1 protein (active)
GTX00214-PRO
ApplicationsFunctional Assay
Product group Proteins / Signaling Molecules
Protein IDP78423
Overview
- SupplierGeneTex
- Product NameHuman CX3CL1 protein (active)
- Delivery Days Customer9
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- ConjugateUnconjugated
- Protein IDP78423
- Protein NameFractalkine
- Scientific DescriptionThis gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202