Human DARPP32 Ready-To-Use IHC Kit
IHC0670H
CategoryIHC
Product group Diagnostic
Overview
- SupplierBioss
- Product NameHuman DARPP32 Ready-To-Use IHC Kit
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Scientific DescriptionDARPP-32 is a dopamine (DA) and AMP-regugated ~32 kDa phosphoprotein that is associated with dopaminoceptive neurons. The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac®.
- UNSPSC41116112