Human DR3/TNFRSF25 Protein (DR3-HM603)

KACTUS

Human DR3/TNFRSF25 Protein (DR3-HM603)

9

Research Use Only

>95%

Death Receptor 3 (DR3), also known as TNFRSF25, TRAMP, LARD, or WSL-1, is a death-domain-containing TNF-family receptor that, like its closest paralog TNFR1, binds the adaptor molecule TRADD through its cytoplasmic death domain. TRADD recruitment endows DR3 with dual-signaling capability to activate NF-kappaB and MAP-kinase signaling or alternatively trigger caspase activation and programmed cell death.

-80°C

12352202