Cell proliferation effect of GTX00422-pro Human EPO protein (active), cell viability was measured by cell Counting Kit-8 (CCK-8). (A) Unstimulated TF-1 cells cultured in RPMI-1640 for 72hrs. (B) TF-1 cells cultured in RPMI-1640, stimulated with 5 ng/ml EPO for 72hrs.
Cell proliferation effect of GTX00422-pro Human EPO protein (active), cell viability was measured by cell Counting Kit-8 (CCK-8). (A) Unstimulated TF-1 cells cultured in RPMI-1640 for 72hrs. (B) TF-1 cells cultured in RPMI-1640, stimulated with 5 ng/ml EPO for 72hrs.
Human EPO protein (active)
GTX00422-PRO
ApplicationsFunctional Assay, ELISA
Product group Proteins / Signaling Molecules
Protein IDP01588
Overview
- SupplierGeneTex
- Product NameHuman EPO protein (active)
- Delivery Days Customer9
- ApplicationsFunctional Assay, ELISA
- CertificationResearch Use Only
- ConjugateUnconjugated
- Protein IDP01588
- Protein NameErythropoietin
- Scientific DescriptionThis gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202