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3μg Human EVI1 protein (GTX67549-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Human EVI1 protein, His tag

Name: Human EVI1 protein, His tag
SKU: GTX67549-PRO_G10
Availability: BackOrder

GTX67549-PRO

Protein IDQ03112

Product group Proteins / Signaling Molecules

Overview

Supplier
GeneTex
Product Name
Human EVI1 protein, His tag
Delivery Days Customer
9
Certification
Research Use Only
Concentration
0.25 mg/ml
Conjugate
Unconjugated
Gene ID2122
Target name
MECOM
Target description
MDS1 and EVI1 complex locus
Target synonyms
AML1-EVI-1, EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3, RUSAT2, histone-lysine N-methyltransferase MECOM, AML1-EVI-1 fusion protein, MDS1 and EVI1 complex locus protein EVI1, MDS1 and EVI1 complex locus protein MDS1, PR domain 3, ecotropic virus integration site 1 protein homolog, myelodysplasia syndrome-associated protein 1, oncogene EVI1, zinc finger protein Evi1
Protein IDQ03112
Protein Name
Histone-lysine N-methyltransferase MECOM
Scientific Description
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
41116100
Species
Human