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WB analysis of GTX00269-pro Human Factor B protein (active).
WB analysis of GTX00269-pro Human Factor B protein (active).
WB analysis of GTX00269-pro Human Factor B protein (active).

Human Factor B protein (active)

Research Use Only
GTX00269-PRO
GeneTex
ApplicationsFunctional Assay
Product group Proteins / Signaling Molecules
Protein IDP00751
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Human Factor B protein (active)
  • Delivery Days Customer
    9
  • Applications
    Functional Assay
  • Certification
    Research Use Only
  • Conjugate
    Unconjugated
  • Protein IDP00751
  • Protein Name
    Complement factor B
  • Scientific Description
    This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5 end of the gene for complement component 2. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352202