Bio-Connect

Human Factor H/CFH Protein (CFH-HM101)

CFH-HM101
KACTUS
Product group Proteins
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Overview

  • Supplier
    KACTUS
  • Product Name
    Human Factor H/CFH Protein (CFH-HM101)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202