Human FAM3D Protein (FAM-HM23D)

KACTUS

Human FAM3D Protein (FAM-HM23D)

9

Research Use Only

>95%

Protein FAM3D

The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.

-20°C or -80°C,-80°C

12352202