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Human FGFR3 recombinant protein (ECD) (Fc-His-tagged, C-ter)

Research Use Only
ARG70258
Arigo Biolaboratories
Product group Molecular Biology
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    Human FGFR3 recombinant protein (ECD) (Fc-His-tagged, C-ter)
  • Delivery Days Customer
    23
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
  • Storage Instruction
    -20°C
  • UNSPSC
    41116133