Human GCGR/Glucagon receptor Protein (GCR-HM40R)
GCR-HM40R
Protein IDP47871
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameHuman GCGR/Glucagon receptor Protein (GCR-HM40R)
- Delivery Days Customer9
- Estimated Purity>95%
- FormulationLyophilized
- Protein IDP47871
- Protein NameGlucagon receptor
- Scientific DescriptionThe pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202