3 microg of GTX67031-pro Human Growth hormone Receptor protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
Human Growth hormone Receptor protein (active)
GTX67031-PRO
ApplicationsFunctional Assay
Product group Proteins / Signaling Molecules
Protein IDP10912
Overview
- SupplierGeneTex
- Product NameHuman Growth hormone Receptor protein (active)
- Delivery Days Customer9
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Protein IDP10912
- Protein NameGrowth hormone receptor
- Scientific DescriptionThis gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202