3microg Human GSKIP protein (GTX68514-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
3microg Human GSKIP protein (GTX68514-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Human GSKIP protein, His tag
GTX68514-PRO
Overview
- SupplierGeneTex
- Product NameHuman GSKIP protein
- Delivery Days Customer9
- Concentration1 mg/ml
- FormulationLiquid
- Protein IDQ9P0R6
- Protein NameGSK3B-interacting protein
- Scientific DescriptionThis gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202