Human Hepcidin/HAMP Protein (HEP-HE601)

KACTUS

Human Hepcidin/HAMP Protein (HEP-HE601)

9

>95%

Lyophilized

Hepcidin

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

-20°C or -80°C,-80°C

12352202