Human HNMT ELISA Kit

Arigo Biolaboratories

Human HNMT ELISA Kit

23

ELISA

62.5 pg/ml - 4,000 pg/ml

Intra-Assay CV: 4.9%Inter-Assay CV: 4.7%

15 pg/ml

~ 5 hours

Research Use Only

HRP

Histamine N-methyltransferase

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

2°C to 8°C

41116100

Human