Human HRG / HPRG ELISA Kit

Arigo Biolaboratories

Human HRG / HPRG ELISA Kit

23

ELISA

Intra-Assay CV: 4.9%Inter-Assay CV: 7.0%

78 pg/ml

~ 5 hours

Research Use Only

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the proteins effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [provided by RefSeq, Nov 2014]

2°C to 8°C

41116133