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Human IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker)(IgD26), 1mg/mL [26628-22-8]

Human IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker)(IgD26), 1mg/mL [26628-22-8]

Research Use Only
BNUM2097
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetIGHD
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Overview

  • Supplier
    Biotium
  • Product Name
    Human IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker)(IgD26), 1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    IgD26
  • Concentration
    1 mg/ml
  • Gene ID3495
  • Target name
    IGHD
  • Target description
    immunoglobulin heavy constant delta
  • Target synonyms
    constant region of heavy chain of IgD
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01880
  • Protein Name
    Immunoglobulin heavy constant delta
  • Scientific Description
    Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203