Human IgG Immunoglobulin(B33/20), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

Human IgG Immunoglobulin(B33/20), CF405S conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

B33/20

0.1 mg/ml

Other Conjugate

IGHG1

immunoglobulin heavy constant gamma 1 (G1m marker)

constant region of heavy chain of IgG1; immunoglobulin gamma 1 (Gm marker)

Mouse

IgG1

Immunoglobulin heavy constant gamma 1

Recognizes a protein of 75 kDa, identified as I3 heavy chain of human immunoglobulins. Its epitope maps in CH2 domain of Fc region of IgG. It reacts with all sub-classes of I3 chain of human immunoglobulins. It does not cross-react with I+/- (IgA), micro (IgM), Imicro (IgE), or I (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203