![Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(R1/69), 1mg/mL [26628-22-8] Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(R1/69), 1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-703.jpeg)
Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(R1/69), 1mg/mL [26628-22-8]

BNUM2096
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetIGHM
Overview
- SupplierBiotium
- Product NameHuman IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(R1/69), 1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDR1/69
- Concentration1 mg/ml
- Gene ID3507
- Target nameIGHM
- Target descriptionimmunoglobulin heavy constant mu
- Target synonymsAGM1; constant region of heavy chain of IgM; immunoglobulin mu chain; MU; VH
- HostMouse
- IsotypeIgG1
- Protein IDP20769
- Protein NameImmunoglobulin heavy constant mu
- Scientific DescriptionRecognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstroms macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203