Human IL-1 RAcP, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human IL-1 RAcP / IL-1 R3 Protein, Fc Tag
ILP-H5256
Product group Proteins / Signaling Molecules
Overview
- SupplierACRObiosystems
- Product NameHuman IL-1 RAcP / IL-1 R3 Protein, Fc Tag
- Delivery Days Customer4
- Category SupplierCytokines&Growth Factors
- CertificationResearch Use Only
- Estimated Purity95%
- FormatPowder
- Scientific DescriptionCharacteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 65.7 kDa. The protein migrates as 75-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Description: Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
- Shelf life instruction● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- SourceHuman IL-1 RAcP, Fc Tag (ILP-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3).
- Storage Instruction-20℃
- UNSPSC12352202