Human IL-10 R alpha Protein (IL1-HM4RA)

KACTUS

Human IL-10 R alpha Protein (IL1-HM4RA)

9

Research Use Only

>95%

Interleukin-10 receptor subunit alpha

The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johnes disease (JD). JD is a chronic enteritis in cattle caused by Mycobacterium avium subsp. paratuberculosis (MAP) and is responsible for significant economic losses to the dairy industry. Several candidate genes including IL10RA have been found to be associated with JD.

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12352202