Human IL-2 R beta&IL-2 R gamma Protein (ILR-HM2BG)

KACTUS

Human IL-2 R beta&IL-2 R gamma Protein (ILR-HM2BG)

9

Research Use Only

>95%

Interleukin-2 receptor subunit beta

Wilms tumor 1 (WT1) is a transcription factor which plays a major role in cell proliferation, differentiation, survival, and apoptosis. WT1 was first identified as a tumor suppressor gene in Wilms tumor. The expression of survival signaling genes, IL-2, IL-2RB, and IL-2RG, was also suppressed after WT1-siRNA treatment. In addition, the WT1 silencing also inhibited the S phase of the cell cycle and induced cell death.Moreover, transcriptional modulation of IL-2, IL-2RB, and IL2-2RG expression by WT1 was likely involved in this phenotypic change.

-20°C or -80°C,-80°C

12352202