Human IL-21R Protein (ILR-HM221)
ILR-HM221
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameHuman IL-21R Protein (ILR-HM221)
- Delivery Days Customer9
- Estimated Purity>95%
- Scientific DescriptionIL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORgammat expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker in RM B cells, a feature associated with increased apoptosis and a reduced number of these cells in the circulation.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202