Human IL1 Receptor 2 protein, His tag (active)

GeneTex

Human IL1 Receptor 2 protein, His tag (active)

9

Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED50 for this effect is less or equal to 400 ng/ml with IL-1 beta.

Functional Assay

Research Use Only

0.5 mg/ml

Unconjugated

IL1R2

interleukin 1 receptor type 2

CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, interleukin-1 receptor type 2, CD121 antigen-like family member B, IL-1 type II receptor, IL-1R-beta, antigen CDw121b, interleukin-1 receptor beta, interleukin-1 receptor type II, type II interleukin-1 receptor, beta

Interleukin-1 receptor type 2

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]

-20°C or -80°C,2°C to 8°C

41116100

Human