Human IL10 recombinant protein (Active) (His-tagged, C-ter)
ARG70032
ApplicationsOther Application
Product group Proteins / Signaling Molecules
Protein IDP22301
Overview
- SupplierArigo Biolaboratories
- Product NameHuman IL10 recombinant protein (Active) (His-tagged, C-ter)
- Delivery Days Customer23
- ApplicationsOther Application
- CertificationResearch Use Only
- Estimated Purity>98%
- Protein IDP22301
- Protein NameInterleukin-10
- Scientific DescriptionThe protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
- Storage Instruction-20°C
- UNSPSC12352202