Human IL17A / IL17F Heterodimer ELISA Kit

Arigo Biolaboratories

Human IL17A / IL17F Heterodimer ELISA Kit

23

ELISA

Intra-Assay CV: < 10%Inter-Assay CV: < 10%

0.08 ng/ml

Not react with Human IL17B, IL17C, IL17D, IL17E, IL17RC, IL17RD, IL10, IL12 and IL16.

~ 3.5 hours

Research Use Only

IL17A: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]IL17F: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]

2°C to 8°C

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