Human IL17RA recombinant protein (Active) (ECD) (His-tagged, C-ter)

Arigo Biolaboratories

Human IL17RA recombinant protein (Active) (ECD) (His-tagged, C-ter)

23

Functional Assay, Other Application

Research Use Only

>95%

Interleukin-17 receptor A

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]

-20°C

12352202