Human IL6R alpha recombinant protein (His-tagged, C-ter)

Arigo Biolaboratories

Human IL6R alpha recombinant protein (His-tagged, C-ter)

23

Binding activity test: Measured by its binding ability in a functional ELISA. Immobilized Human IL6R at 1 ug/ml (100 microl/well) can bind Human IL-6 with a linear range of 2-15ng/ml.

Other Application

Research Use Only

>92%

IL6R

interleukin 6 receptor

CD126, HIES5, IL-1Ra, IL-6R, IL-6R-1, IL-6RA, IL6Q, IL6QTL, IL6RA, IL6RQ, gp80, interleukin-6 receptor subunit alpha, CD126 antigen, IL-6 receptor subunit alpha, membrane glycoprotein 80

Interleukin-6 receptor subunit alpha

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, May 2011]

-20°C

41116124

Human